Jens Mortansson Jelstrup Nolsøe

My purview is centred on compounds sourced from the marine environment as the foundation and inspiration for synthetic activity. Most importantly, it serves as a hub to engage in multidisciplinary collaborative efforts aimed at deconvoluting molecular mechanisms. The chemical interlocution between environment and organism is of particular interest. A key premiss is that the outward expression of phenotypical trait and affected perturbation is manifest by the secondary metabolites presented in a downstream direction. Consequently, aspects of the environmental imprint become legible by delving into the natural products from the producing organisms. The implicit adaptive strategy with its chemical motifs and gleaned functional traits forms the seed of discovery and innovation. When transferred from one organism to another, commensal secondary metabolites can effect change in phenotypical expression. Thus, in an upstream direction, natural products have the ability to intercede and regulate physiological processes. Within these bidirectional confines I frame my research. My research activities and interests involve carbocyclic and heterocyclic chemistry, organometallic chemistry, method development, asymmetric catalysis, mechanism studies and synthesis of natural products, as well as having a keen attention on the intersect with biochemistry and chemical biology.