Trine Karlsen
Professor
Faculty of Nursing and Health Sciences
Trine Karlsen, M.Sc., Ph.D.
Professor in Health Sciences and an exercise physiologist with experiences ranging from altitude training, elite athletic performance, cardiovascular prevention, clinical studies and institutional leadership.
My current research focus is in exercise and cardiovascular disease.
2025
Cardiac myosin binding protein C correlate with cardiac troponin I during an exercise training program in patients with HFrEF 2025 ESC Heart Failure - Egil Aarstad Riveland, Anastasia Ushakova, Torstein Valborgland, Trine Karlsen, Håvard Dalen, E. Prescott, Torbjørn Omland, A. Linke, M. Halle, M. Marber, Øyvind Ellingsen, Alf Inge Larsen
Effects of exercise training on nitric oxide metabolites in heart failure with reduced or preserved ejection fraction: a secondary analysis of the SMARTEX-HF and OptimEx-Clin trials 2025 European Journal of Preventive Cardiology (EJPC) - Sophia Marie-Theres Dinges, Edzard Schwedhelm, Julia Schoenfeld, Andreas B. Gevaert, Ephraim B. Winzer, Bernhard Haller, Flavia Baldassarri, Axel Pressler, André Duvinage, Rainer H. Böger, Axel Linke, Volker Adams, Burkert Pieske, Frank Edelmann, Håvard Dalen, Torstein Laurits Hole, Alf Inge Larsen, Patrick Feiereisen, Trine Karlsen, Eva Prescott, Øyvind Ellingsen, Emeline M. Van Craenenbroeck, Martin Halle, Stephan Mueller
2024
Exercise training and high-sensitivity cardiac troponin-I in patients with heart failure with reduced ejection fraction 2024 ESC Heart Failure - Egil Aarstad Riveland, Torstein Valborgland, Anastasia Ushakova, Øyvind Skadberg, Trine Karlsen, Torstein Laurits Hole, Asbjørn Støylen, Håvard Dalen, Vibeke Videm, Elias Koppen, Axel Linke, Charles Delagardelle, Emeline M. Van Craenenbroeck, Paul Beckers, Eva Prescott, Martin Halle, Torbjørn Omland, Øyvind Ellingsen, Alf Inge Larsen
2023
Determinants and reference values for blood volume and total hemoglobin mass in women and men 2023 American Journal of Hematology - Laura Oberholzer, David Montero, Paul Robach, Christoph Siebenmann, Camilla Koch Ryrsøe, Thomas C. Bonne, Andreas Breenfeldt Andersen, Jacob Bejder, Trine Karlsen, Elisabeth Edvardsen, Bent Rønnestad, Håvard Hamarsland, Ana C. Cepeda-Lopez, Jörn Rittweger, Gunnar Treff, Christoph Ahlgrim, Nicki Winfield Almquist, Jostein Hallén, Carsten Lundby
2022
Moderate continuous or high intensity interval exercise in heart failure with reduced ejection fraction: Differences between ischemic and non-ischemic etiology 2022 American Heart Journal Plus: Cardiology Research and Practice (AHJ Plus) - Martin Halle, Eva Bossano Prescott, Emeline M Van Craenenbroeck, Paul Beckers, Vibeke Videm, Trine Karlsen, Patrick Feiereisen, Ephraim B. Winzer, Norman Mangner, Martin Snoer, Jeffrey W. Christle, Håvard Dalen, Asbjørn Støylen, Katrin Esefeld, Melanie Heitkamp, Bianca Spanier, Linke Axel, Øyvind Ellingsen, Charles Delagardelle
No Effect of Calanus Oil on Maximal Oxygen Uptake in Healthy Participants: A Randomized Controlled Study. 2022 International Journal of Sport Nutrition & Exercise Metabolism - Lucas Christian Tauschek, Ragnhild Røsbjørgen, Håvard Dalen, Terje Larsen, Trine Karlsen
Exercise and obstructive sleep apnoea: a 24-week follow-up study 2022 BMJ Open sport & exercise medicine - Trine Karlsen, Morten Engstrøm, Sigurd Loe Steinshamn
2021
Blood Volume, Hemoglobin Mass, and Peak Oxygen Uptake in Older Adults: The Generation 100 Study 2021 Frontiers in Sports and Active Living - Kari Margrethe Lundgren, Nils Petter Aspvik, Knut Asbjørn Rise Langlo, Tonje Bjørndal Braaten, Ulrik Wisløff, Dorthe Stensvold, Trine Karlsen
Exercise training and high-sensitivity cardiac troponin T in patients with heart failure with reduced ejection fraction 2021 ESC Heart Failure - Elias Koppen, Torbjørn Omland, Alf Inge Larsen, Trine Karlsen, Axel Linke, Eva Irene Bossano Prescott, Martin Halle, Håvard Dalen, Charles Delagardelle, Torstein Hole, Emeline M. van Craenenbroeck, Paul Beckers, Øyvind Ellingsen, Patrick Feiereisen, Torstein Valborgland, Vibeke Videm
2020
Intensity Control During Block-Periodized High-Intensity
Training: Heart Rate and Lactate Concentration During Three Annual Seasons in World-Class Cross-Country Skiers 2020 Frontiers in Sports and Active Living - Trine Karlsen, Guro Strøm Solli, Svein Tore Samdal, Øyvind Sandbakk
2019
Baseline and Exercise Predictors of VO2peak in Systolic Heart Failure Patients: Results from SMARTEX-HF. 2019 Medicine & Science in Sports & Exercise - Trine Karlsen, Vibeke Videm, Martin Halle, Øyvind Ellingsen, Asbjørn Støylen, Håvard Dalen, Charles Delagardelle, Alf Inge Larsen, Torstein Hole, Alessandro Mezzani, Emeline M. Van Craenenbroeck, Paul Beckers, Axel Pressler, Jeffrey W. Christle, Ephraim Winzer, Norman Mangner, Felix Woitek, Robert Höllriegel, Martin Snoer, Patrick Feiereisen, Torstein Valborgland, Axel Linke, Eva Irene Bossano Prescott
2017
High Intensity Interval Training for Maximizing Health Outcomes 2017 Progress in cardiovascular diseases - Trine Karlsen, Inger Lise Aamot, Mark Haykowsky, Øivind Rognmo
Upper arm venous compliance and fitness in stable coronary artery disease patients and healthy controls 2017 Clinical Physiology and Functional Imaging - Ingeborg Megård Leinan, Inger Lise Aamot, Asbjørn Støylen, Trine Karlsen, Ulrik Wisløff
High-intensity interval training improves obstructive sleep apnoea 2017 BMJ Open sport & exercise medicine - Trine Karlsen, Bjarne Nes, Arnt Erik Tjønna, Morten Engstrøm, Asbjørn Støylen, Sigurd Loe Steinshamn
The Combined Association of Skeletal Muscle Strength and Physical Activity on Mortality in Older Women: The HUNT2 Study 2017 Mayo Clinic proceedings - Trine Karlsen, Javaid Nauman, Håvard Dalen, Arnulf Langhammer, Ulrik Wisløff
High-Intensity Interval Training in Patients with Heart Failure with Reduced Ejection Fraction 2017 Circulation - Øyvind Ellingsen, Martin Halle, Viviane Conraads, Asbjørn Støylen, Håvard Dalen, Charles Delagardelle, Alf Inge Larsen, Torstein Hole, Alessandro Mezzani, Emeline M. Van Craenenbroeck, Vibeke Videm, Paul Beckers, Jeffrey W. Christle, Ephraim Winzer, Norman Mangner, Felix Woitek, Robert Höllriegel, Axel Pressler, Tea Monk-Hansen, Martin Snoer, Patrick Feiereisen, Torstein Valborgland, John Kjekshus, Rainer Hambrecht, Stephan Gielen, Trine Karlsen, Eva Prescott, Axel Linke
Effects of upper-body sprint-interval training on strength and endurance capacities in female cross-country skiers 2017 PLOS ONE - Kristine Vandbakk, Boye Welde, Andrea Hovstein Kruken, Julia Kathrin Baumgart, Gertjan Ettema, Trine Karlsen, Øyvind Sandbakk
2016
Safety of the CO-Rebreathing method in patients with coronary artery disease 2016 Medicine & Science in Sports & Exercise - Trine Karlsen, Ingeborg Megård Leinan, Inger Lise Aamot, Håvard Dalen, Asbjørn Støylen
Comparison of three popular exercise modalities on VO2max in overweight and obese 2016 Medicine & Science in Sports & Exercise - Fredrik Hjulstad Bækkerud, Frederic Solberg, Ingeborg Megård Leinan, Ulrik Wisløff, Trine Karlsen, Øivind Rognmo
Living altitude influences endurance exercise performance change over time at altitude 2016 Journal of applied physiology - Robert F Chapman, Trine Karlsen, RL Ge, James Stray-Gundersen, Benjamin D Levine
Long-term exercise adherence after high-intensity interval training in cardiac rehabilitation: a randomized study 2016 Physiotherapy Research International - Inger Lise Aamot, Trine Karlsen, Håvard Dalen, Asbjørn Støylen
2015
How to Be 80 Year Old and Have a VO2max of a 35 Year Old 2015 Case Reports in Medicine - Trine Karlsen, Ingeborg Megård Leinan, Fredrik Hjulstad Bækkerud, Kari Margrethe Lundgren, Atefe R Tari, Sigurd Loe Steinshamn, Asbjørn Støylen, Øivind Rognmo
The effects of upper body sprint intervals on upper body strength and aerobic capacity in female cross-country skiers 20th annual Congress of the EUROPEAN COLLEGE OF SPORT SCIENCE 24th - 27th June 2015, Malmö – Sweden BOOK OF ABSTRACTS 2015 - Andrea Kruken, Kristine Vandbakk, Trine Karlsen, Øyvind Sandbakk
Sport-Specific Physiological Adaptations in Highly Trained Endurance Athletes 2015 Medicine & Science in Sports & Exercise - Kari Margrethe Lundgren, Trine Karlsen, Øyvind Sandbakk, Philip E James, Arnt Erik Tjønna
Effect of change in vo<inf>2</inf>max on daily total energy expenditure in a cohort of norwegian men: A randomized pilot study 2015 Open Cardiovascular Medicine Journal - Nina Zisko, Dorthe Stensvold, Katrine Hordnes Slagsvold, Øivind Rognmo, Javaid Nauman, Ulrik Wisløff, Trine Karlsen
Acute dietary nitrate supplementation improves arterial endothelial function at high altitude: A double-blinded randomized controlled cross over study 2015 Nitric oxide - Emily Bakker, Harald Kåre Engan, Alexander Patrician, Erika Schagatay, Trine Karlsen, Ulrik Wisløff, Svein Erik Gaustad
A cross sectional study of arm venous compliance in fit healthy subjects. 2015 Journal of Cardiovascular Research - Ingeborg Megård Leinan, Øystein Grønnevik, Asbjørn Støylen, Ulrik Wisløff, Trine Karlsen
2014
Does rating of perceived exertion result in target exercise intensity during interval training in cardiac rehabilitation? A study of the Borg scale versus a heart rate monitor 2014 Journal of Science and Medicine in Sport - Inger-Lise Aamot, Siv Hege Forbord, Trine Karlsen, Asbjørn Støylen
Defining the "dose" of altitude training: How high to live for optimal sea level performance enhancement 2014 Journal of applied physiology - Robert Sedgwick Chapman, Trine Karlsen, Geir Kåre Resaland, RL Ge, Matthew P. Harber, Sarah Witkowski, James Stray-Gundersen, Ben Levine
Home-based versus hospital-based high-intensity interval training in cardiac rehabilitation: A randomized study 2014 European Journal of Preventive Cardiology (EJPC) - Inger Lise Aamot, Siv Hege Forbord, Kjersti Gustad, Vibeke Løckra, Andreas Stensen, Astrid Tarlebø Berg, Håvard Dalen, Trine Karlsen, Asbjørn Støylen
2013
Effect of lower extremity functional electrical stimulation pulsed isometric contractions on arm cycling peak oxygen uptake in spinal cord injured individuals 2013 Journal of Rehabilitation Medicine - Berit Brurok, Tom Tørhaug, Trine Karlsen, Gunnar Leivseth, Jan Helgerud, Jan Hoff
2012
Maksimal forventet hjertefrekvens 2012 Tidsskrift for Den norske legeforening (Tidsskriftet) - Asbjørn Støylen, Bjarne Martens Nes, Trine Karlsen
Age-predicted maximal heart rate in healthy subjects: The HUNT Fitness Study 2012 Scandinavian Journal of Medicine & Science in Sports - Bjarne Martens Nes, Imre Janszky, Ulrik Wisløff, Asbjørn Støylen, Trine Karlsen
Effect of leg vascular occlusion on arm cycling peak oxygen uptake in spinal cord-injured individuals 2012 Spinal Cord - Berit Brurok, Tom Tørhaug, Gunnar Leivseth, Trine Karlsen, Jan Helgerud, Jan Hoff
Exercise-Training Intervention Studies in Competitive Swimming 2012 Sports Medicine - Stian Thoresen Aspenes, Trine Karlsen
2011
Effect of aerobic high-intensity hybrid training on stroke volume and peak oxygen consumption in men with spinal cord injury 2011 American Journal of Physical Medicine & Rehabilitation - Berit Brurok, Jan Helgerud, Trine Karlsen, Gunnar Leivseth, Jan Hoff
Interval and Strength Training in CAD Patients 2011 International Journal of Sports Medicine (IJSM) - Jan Helgerud, Trine Karlsen, WY Kim, Kjetil L Høydal, Asbjørn Støylen, H Pedersen, L Brix, S Ringgaard, J Kværness, Jan Hoff
2010
Hyperoxic interval training in chronic obstructive pulmonary disease patients with oxygen desaturation at peak exercise 2010 Scandinavian Journal of Medicine & Science in Sports - Jan Helgerud, Siri Bjørgen, Trine Karlsen, Vigdis Schnell Husby, Sigurd Loe Steinshamn, Russell Richardson, Jan Hoff
2009
Maximal Strength Training Restores Walking Mechanical Effeciency in Heart Patients 2009 International Journal of Sports Medicine (IJSM) - Trine Karlsen, Jan Helgerud, Asbjørn Støylen, N Lauritsen, Jan Hoff
2008
Training is Medicine; Endurance and Strength Training in Coronary Artery Disease and Health 2008 - Trine Karlsen, Jan Hoff, Jan Helgerud
Aerobic interval training improves VO2 peak in coronary artery disease patients; no additional effect from hyperoxia 2008 Scandinavian Cardiovascular Journal - Trine Karlsen, Jan Hoff, Asbjørn Støylen, Mie Cappelen Skovholt, Kari Gulbrandsen Aarhus, Jan Helgerud
2007
Patients with coronary artery- or chronic obstructive pulmonary disease walk with mechanical inefficiency 2007 Scandinavian Cardiovascular Journal - Kjetil Laurits Høydal, Jan Helgerud, Trine Karlsen, Asbjørn Støylen, Sigurd Loe Steinshamn, Jan Hoff
Aerobic high-intensity intervals improve VO2max more than moderate training 2007 Medicine & Science in Sports & Exercise - Jan Helgerud, Kjetil Laurits Høydal, Eivind Wang, Trine Karlsen, P Berg, M Bjerkaas, T Simonsen, C Helgesen, N Hjorth, R Bach, Jan Hoff
2006
Urine acid-base compensation at simulated moderate altitude 2006 High Altitude Medicine & Biology - RL Ge, T. G. Babb, Mark Sivieri, Geir Kåre Resaland, Trine Karlsen, Jim Stray-Gundersen, Ben Levine
2002
Determinants of erythropoietin release in response to short-term hypobaric hypoxia 2002 Journal of applied physiology - Ben Levine, Geir Kåre Resaland, Trine Karlsen, RL Ge, Sarah Witkowski, Y Zhang, C Alfrey, Mark Sivieri, M Harber, Jim Stray-Gundersen
2025
Chapter 7. Environmental Considerations for Exercise Prescription: Exercise in Hot Environments. In: Ozemek, C., Bonikowske, A., Christle, J., & Gallo, P. (Eds.), ACSM's guidelines for exercise testing and prescription (12th ed, pp 250-273) 2025 - Rebecca L Stearns, M Healy, Trine Karlsen, Michael R Szymanski, Douglas J Casa
2020
The effect of Calanus Finmarchicus oil (Calanus® Oil ) on maximal oxygen uptake: a randomized controlled study 2020 American College of Sports Medicine Annual Congress - Trine Karlsen, Lucas Taucheck, Ragnhild Røsbjørgen, Håvard Dalen, Terje Larsen
2016
On the effects of upper-body sprint-interval training on maximal strength and aerobic Power in female cross-country skiers 2016 7th International Congress on Science and Skiing - Boye Welde, Kristine Vandbakk, Andrea Hovstein, Julia Kathrin Baumgart, Gerardus Johannes C Ettema, Trine Karlsen, Øyvind Sandbakk
2014
Comparing cardiorespiratory fitness across populations 2014 Chest - Bjarne Nes, Trine Karlsen, Øivind Rognmo, Ulrik Wisløff
2012
Cardiovascular fitness is associated with venous compliance in healthy subjects 2012 Europrevent - Ingeborg Leinan, Asbjørn Støylen, Ulrik Wisløff, Trine Karlsen
Total Hemoglobin Mass, Erythrocyte Volume and VO2max in Overweight and Normal Weight Healthy Subjects 2012 Medicine & Science in Sports & Exercise - Trine Karlsen, Ingeborg Leinan, Fredrik H Bækkerud, Frederic Solberg, Asbjørn Støylen, Øivind Rognmo, Ulrik Wisløff
Implementation of aerobic interval training in cardiac rehabilitation: a randomized clinical study 2012 Europrevent - Inger Lise Aamot, Siv Hege Forbord, Vibeke Løckra, Kjersti Gustad, Andreas Stensen, Astrid Tarlebø Berg, Håvard Dalen, Trine Karlsen, Asbjørn Støylen
Cardiovascular Fitness is Associated with Venous Compliance in Healthy Subjects 2012 Medicine & Science in Sports & Exercise - Ingeborg Leinan, Øystein Gronnevik, Asbjørn Støylen, Ulrik Wisloff, Trine Karlsen
Feasibility of aerobic interval training in cardiac rehabilitation 2012 59th annual meeting ACSM - Inger Lise Aamot, Siv Hege Forbord, Vibeke Løckra, Kjersti Gustad, Andreas Stensen, Astrid Tarlebø Berg, Håvard Dalen, Trine Karlsen, Asbjørn Støylen
Exercise adherence after aerobic interval training in patients with coronary artery disease 2012 Annual meeting European college of Sport Sciences - Inger Lise Aamot, Trine Karlsen, Håvard Dalen, Asbjørn Støylen
High-intensity aerobic interval training in cardiac rehabilitation: a matter of mode? 2012 3rd World Congress of Exercise is Medicine - Inger Lise Aamot, Siv Hege Forbord, Vibeke Løckra, Kjersti Gustad, Andreas Stensen, Astrid Tarlebø Berg, Håvard Dalen, Trine Karlsen, Asbjørn Støylen
Feasibility Of Aerobic Interval Training In Cardiac Rehabilitation 2012 Medicine & Science in Sports & Exercise - Inger Lise Aamot, Siv Hege Forbord, Vibeke Lockra, Kjersti Gustad, Andreas Stensen, Astrid Tarlebø Berg, Håvard Dalen, Trine Karlsen, Asbjørn Støylen
High-intensity Aerobic Interval Training In Cardiac Rehabilitation: A Matter Of Mode? 2012 Medicine & Science in Sports & Exercise - Inger Lise Aamot, Siv Hege Forbord, Vibeke Lockra, Kjersti Gustad, Andreas Stensen, Astrid Tarlebø Berg, Håvard Dalen, Trine Karlsen, Asbjørn Støylen
Total Hb-Mass, Erythrocyte Volume and VO2max in Overweight and Normal Weight Healthy Subjects 2012 American College of Sports Medicine - Trine Karlsen, Ingeborg Leinan, Fredrik H Bækkerud, Frederic Solberg, Asbjørn Støylen, Ulrik Wisløff, Øivind Rognmo
Six weeks of 10x1 minute of High Intensity Interval Training Increase Plasma Volume and Hemoglobin Mass in Untrained Obese Subjects 2012 The Biomedical Basis of Elite Performance - Trine Karlsen, Frederic Solberg, Ingeborg Leinan, Ulrik Wisløff, Øivind Rognmo, Fredrik H Bækkerud
Maximal Oxygen Uptake in the Fight Against Inactivity? 2012 The Biomedical Basis of Elite Performance - Trine Karlsen, Dorthe Stensvold, Katrine Hordnes, Øivind Rognmo, Ulrik Wisløff, Nina Zisko
Increase in maximal oxygen uptake in the fight against inactivity? 2012 EuroPrevent - Trine Karlsen, Nina Zisko, Katrine Hordnes, Øivind Rognmo, Ulrik Wisløff, Dorthe Stensvold
2011
Effect of leg vascular occlusion on arm cycling peak oxygen uptake in spinal cord injured individuals 2011 Annual conference in American College of Sports Medicine - Berit Brurok, Tom Tørhaug, Gunnar Leivseth, Trine Karlsen, Jan Helgerud, Jan Hoff
Age-Predicted Maximal Heart Rate in 3320 Health Subjects-The HUNT Fitness Study 2011 American college of Sports Medicine - Bjarne Martens Nes, Ulrik Wisløff, Asbjørn Støylen, Trine Karlsen
Age-Predicted Maximal Heart Rate in Healthy Subjects-The HUNT Fitness Study 2011 EuroPrevent Conference - Bjarne Martens Nes, Ulrik Wisløff, Asbjørn Støylen, Trine Karlsen
Cardiovascular fitness and venous compliance 2011 CHFR Synopsium - Ingeborg Leinan, Asbjørn Støylen, Ulrik Wisløff, Trine Karlsen, Grønnevik Øystein
Prediction of maximal heart rate in clinical settings 2011 Norsk Cardiologisk Selskaps Vintermøte - Bjarne Martens Nes, Asbjørn Støylen, Ulrik Wisløff, Trine Karlsen
Self-reported physical activity and aerobic capasity in patients entering cardiac rehabilitation 2011 Årskongress ACSM - Inger Lise Aamot, Trine Karlsen, Asbjørn Støylen
2009
Aerobic Interval Training and Stroke Volume Response in Cardio Vascular Disease Patients 2009 European college of sport science - Jan Helgerud, Trine Karlsen, kim W yong, Kjetil L. Høydal, Asbjørn Støylen, henrik pedersen, Lau Brix, Steffen Ringgaard, jørn kværness, Jan Hoff
2007
VO2peak and Stroke Volume of the heart are enhanced by aerobic high intensity interval hybrid training in Spinal Cord Injured individuals 2007 - Berit Brurok, Jan Helgerud, Trine Karlsen, Jan Hoff, Jan Hoff
2006
Differential Response to Aerobic Endurance Training at Different Intensities 2006 Medicine & Science in Sports & Exercise - Jan Helgerud, Kjetil Laurits Høydal, Eivind Wang, Trine Karlsen, Pål Berg, Marius Bjerkaas, Thomas Simonsen, Cecilie Helgesen, Nina Hjorth, Bach Ragnhild, Jan Hoff
Aerobic Interval Training Breathing 100% O2 Improves VO2peak Equally as Ambient Air Training in Coronary Patients 2006 Medicine & Science in Sports & Exercise - Trine Karlsen, Jan Hoff, Asbjørn Støylen, Jan Helgerud
2001
Optimal altitude for "living high-training low" 2001 American College of sports medicine, 48th annual meeting, 2001 - Geir Kåre Resaland, Sarah Witkowski, Trine Karlsen, Mark Sivieri, Robert Yates, M Harber, G Ri-Li, Ben Levine, Jim Stray-Gundersen
EPO response to 24 hours of artificial hypobaric hypoxia predicts EPO response to natural altitude 2001 American College of sports medicine, 48th annual meeting, 2001 - Geir Kåre Resaland, Ben Levine, Trine Karlsen, Mark Sivieri, G Ri-Li, Sarah Witkowski, Robert Yates, Jim Stray-Gundersen
Individual differences in the relationship between VO2-max and acute moderate hypobaric hypoxia 2001 American College of Sports Medicine, 48th Annual Metting - Trine Karlsen, Jostein Hallén, Jim Stray-Gundersen
2000
No difference in 3-day EPO response to 8, 12 or 16 hours/ day of intermittent hypoxia 2000 American College of sports medicine, 47th annual meeting, 2000 - Geir Kåre Resaland, Jim Stray-Gundersen, Trine Karlsen, Sigmund B. Aasen, Cathrine Lind, Kåre Inge Birkeland, Jostein Hallén