Elizabeth Gladys Aarag Fredheim
Førsteamanuensis
Fakultet for sykepleie og helsevitenskap
2025
Antimicrobial Activity of Short Analogues of the Marine Peptide EeCentrocin 1: Synthesis of Lipopeptides and Head-to-Tail Cyclic Peptides and Mechanism of Action Studies 2025 Journal of Peptide Science - Danijela Simonovic, Hymonti Dey, Natascha Johansen, Trude Anderssen, Ida Kristine Østnes Hansen, hege Devold, Terje Vasskog, Hans-Matti Blencke, Frode Jacobsen Øyen, Elizabeth G. Aarag Fredheim, Tor Haug, Morten B. Strøm
2024
Antimicrobial activities and mechanisms of action of peptide analogues of marine origin 2024 - Hymonti Dey, Tor Haug, Hans-Matti Blencke, Elizabeth G. Aarag Fredheim, Morten B. Strøm
2022
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications 2022 International Journal of Molecular Sciences - Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke, Trude Anderssen, Morten B. Strøm, Tor Haug
2021
The chemotherapeutic drug methotrexate selects for antibiotic resistance 2021 EBioMedicine - Jonina Gudmundsdottir, Elizabeth G. Aarag Fredheim, Catharina I.M. Koumans, Joachim Hegstad, Po-Cheng Tang, Dan I. Andersson, Ørjan Samuelsen, Pål Jarle Johnsen
2020
Liposomal delivery of antibiotic loaded nucleic acid nanogels with enhanced
drug loading and synergistic anti-inflammatory activity against S. aureus
intracellular infections 2020 Journal of Controlled Release - Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Mona Johannessen, Natasa Skalko-Basnet
Dominance between plasmids determines the extent of biofilm formation 2020 Frontiers in Microbiology - João Alves Gama, Elizabeth G. Aarag Fredheim, Francois Pierre Alexandre Cléon, Ana Maria Reis, Rita Zilhão, Francisco Dionisio
Identification of surface proteins in a clinical Staphylococcus haemolyticus isolate by bacterial surface shaving 2020 BMC Microbiology - Runa Wolden, Maria Pain, Roger Karlsson, Anders Karlsson, Elizabeth G. Aarag Fredheim, Jorunn Pauline Cavanagh
2019
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model 2019 APMIS - Journal of Pathologiy, Microbiology and Immunology - Hildegunn Norbakken Granslo, Elizabeth Aarag, Eirin Esaiassen, Lars Christophersen, Peter Østrup Jensen, Tom Eirik Mollnes, Claus Moser, Trond Flægstad, Claus Klingenberg, Jorunn Pauline Cavanagh
2018
Amphipathic sulfonamidobenzamides mimicking small antimicrobial marine natural products; investigation of antibacterial and anti-biofilm activity against antibiotic resistant clinical isolates. 2018 Bioorganic & Medicinal Chemistry - Elizaveta Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag, Silje Lauksund, Klara Stensvåg, Morten B. Strøm
Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli. 2018 Nature Communications - Nicole L. Podnecky, Elizabeth Aarag, Julia Maria Kloos, Vidar Sørum, Raul Primicerio, Adam Paul Roberts, Daniel E. Rozen, Ørjan Samuelsen, Pål Jarle Johnsen
2017
Antibacterial and anti-biofilm activity of novel marine natural product mimics 2017 - Ekaterina Mishchenko, Johanna U Ericson Sollid, Hans-Matti Blencke, Tor Haug, Elizabeth Aarag, Klara Stensvåg
2016
Coagulase-negative staphylococci in southern brazil: Looking toward its high diversity 2016 Revista da Sociedade Brasileira de Medicina Tropical - Caio Fernando de Oliveira, Jorunn Pauline Cavanagh, Elizabeth Aarag, Keli Cristine Reiter, Alexandre Rieger, Claus Klingenberg, Pedro Alves D'Azevedo, Johanna U Ericson Sollid
Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria. 2016 Bioorganic & Medicinal Chemistry - Elizaveta Mikhailovna Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth G Aarag Fredheim, Silje Lauksund, Klara Stensvåg, Morten Bøhmer Strøm
Synthesis and antimicrobial activity of small cationic amphipathic aminobenzamide marine natural product mimics and evaluation of relevance against clinical isolates including ESBL–CARBA producing multi-resistant bacteria 2016 Bioorganic & Medicinal Chemistry - Elizaveta Mikhailovna Igumnova, Ekaterina Mishchenko, Tor Haug, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag, Reidunn Silje Lauksund, Klara Stensvåg, Morten B. Strøm
Antimicrobial susceptibility and body site distribution of community isolates of coagulase-negative staphylococci 2016 APMIS - Journal of Pathologiy, Microbiology and Immunology - Jorunn Pauline Cavanagh, Runa Wolden, Philipp Heise, Eirin Esaiassen, Claus Klingenberg, Elizabeth Aarag
2015
Colonisation and interaction between S. epidermidis and S. aureus in the nose and throat of healthy adolescents. 2015 European Journal of Clinical Microbiology and Infectious Diseases - Elizabeth Aarag, Trond Flægstad, Fatemeh Askarian, Claus Klingenberg
2014
Colonisation and interaction between S. epidermidis and S. aureus in the nose and throat of healthy adolescents 2014 European Journal of Clinical Microbiology and Infectious Diseases - Elizabeth Aarag Fredheim, Trond Flægstad, Fatemeh Askarian, Claus Klingenberg
2013
Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model 2013 Journal of Antimicrobial Chemotherapy - Jorunn Pauline Cavanagh, Hildegunn Norbakken Granslo, Elizabeth Aarag, L Christophersen, Peter Østrup Jensen, Kim Thomsen, Maria Van Gennip, Claus Klingenberg, Trond Flægstad, Claus Moser
Staphylococcus epidermidis biofilms induce lower complement activation in neonates as compared with adults 2013 Pediatric Research - Hildegunn Norbakken Granslo, Claus Klingenberg, Elizabeth A. Fredheim, Ganesh Acharya, Tom Eirik Mollnes, Trond Flægstad
2012
Core genome conservation of Staphylococcus haemolyticus limits sequence based population structure analysis 2012 Journal of Microbiological Methods - Jorunn Pauline Cavanagh, Claus Klingenberg, Anne-Merethe Hanssen, Elizabeth Aarag, Patrice Francois, Jaques Schrenzel, Trond Flægstad, Johanna U Ericson Sollid
2011
Staphylococcus epidermidis polysaccharide intercellular adhesin activates complement 2011 FEMS Immunology and Medical Microbiology - Elizabeth Aarag, Hildegunn Norbakken Granslo, Trond Flægstad, Yngve Figenschau, H Rohde, I Sadovskaya, Tom Eirik Mollnes, Claus Klingenberg
2010
Arginine Catabolic Mobile Element Is Associated With Low Antibiotic Resistance and Low Pathogenicity in Staphylococcus epidermidis From Neonates 2010 Pediatric Research - Hildegunn Norbakken Granslo, Claus Klingenberg, Elizabeth Aarag, Arild Erlend Rønnestad, Tom Eirik Mollnes, Trond Flægstad
2009
Biofilm Formation by Staphylococcus haemolyticus 2009 Journal of Clinical Microbiology - Elizabeth Aarag, Claus Klingenberg, Holger Rohde, S Frankenberger, Petter Gaustad, T Flaegstad, Trond Flaegstad, johanna u ericson Sollid
2008
Biofilm og antibiotikaresistens hos koagulasenegative stafylokokker 2008 Tidsskrift for Den norske legeforening (Tidsskriftet) - Karianne Wiger Gammelsrud, Elizabeth Aarag, Trond Flaegstad, Claus Klingenberg, Hildegunn Thorsteinsen Granslo
Koagulase negative stafylokokker - biofilm og antibiotikaresistens 2008 Tidsskrift for Den norske legeforening (Tidsskriftet) - Hildegunn Norbakken Granslo, K W Gammelsrud, Elizabeth Aarag, Trond Flaegstad, Claus Klingenberg
2005
Coagulase-negative Staphylococcal Sepsis among Neonates: Association between Antibiotic Resistance, Biofilm Formation and the Host Inflammatory Response 2005 The Pediatric Infectious Disease Journal - Claus Klingenberg, Elizabeth Aarag, A Rønnestad, johanna u ericson Sollid, TG Abrahamsen, Gry Kjeldsen, Trond Flaegstad
2024
Combining outer membrane active synthetic antimicrobial peptides with vancomycin or erythromycin increases antibacterial and antibiofilm activities 2024 Eurobiofilms 2024 - Hymonti Dey, Danijela Simonovic, Celine Sarah Marine Richard, Ingrid Sofie Norberg-Schultz Hagen, Natascha Johansen, Frode Jacobsen Øyen, Elizabeth G. Aarag Fredheim, Morten B. Strøm, Roger Simm, Hans-Matti Blencke, Tor Haug
2023
Biofilm-associated traits of human pathogenic Escherichia coli 2023 IBA Annual meeting 2023 - Miriam Kristine Karlsen, Anna Kaarina Pöntinen, Rebecca Ashley Gladstone, Joao Pedro Alves Gama, Elizabeth Gladys Aarag Fredheim
Antimicrobial activity and mode of action study of short cyclic analogues of the marine antimicrobial peptide Turgencin A 2023 The 11th International Conference on Marine Bioprospecting (BIOPROSP_23) - Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke, Morten B. Strøm, Tor Haug
2022
The role of drugs used in cancer chemotherapy as drivers of antibiotic resistance evolution in Escherichia coli 2022 IBA annual meeting 2022 - Pål Jarle Johnsen, Elizabeth G Aarag Fredheim, Ørjan Samuelsen, Klaus Harms
Disclosing the biofilmome of Escherichia coli 2022 Antibiotics and Antibiotic Resistance course - Miriam Kristine Karlsen, Anna Kaarina Pöntinen, João Alves Gama, Rebecca Ashley Gladstone, Vidar Sørum, Elizabeth G. Aarag Fredheim
Disclosing the biofilmome of Escherichia coli 2022 EuroBioFilms conference 2022 - Miriam Kristine Karlsen, Anna Kaarina Pöntinen, João Alves Gama, Rebecca Ashley Gladstone, Vidar Sørum, Elizabeth G. Aarag Fredheim
Disclosing the biofilmome of Escherichia coli 2022 IBA Annual meeting - Miriam Kristine Karlsen, Anna Kaarina Pöntinen, João Alves Gama, Rebecca Ashley Gladstone, Vidar Sørum, Elizabeth G. Aarag Fredheim
Investigation of the antimicrobial activity and proteolytic stability
of the short analogues of the marine peptide EeCentrocin 1 2022 Antibiotics and Antibiotic Resistance Workshop - Danijela Simonovic, Hymonti Dey, Natascha Johansen, Trude Anderssen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Tor Haug, Morten B. Strøm
Antimicrobial Activity and Mode of Action Study of Short
Analogues of The Marine Antimicrobial Peptide Turgencin A 2022 Antibiotics and Antibiotic Resistance Workshop - Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke, Morten B. Strøm, Tor Haug
2021
Investigation of the antimicrobial activity and proteolytic stability of the short analogues of the marine peptide EeCentrocin 1 2021 Infection Biology and Antimicrobials (IBA) annual meeting - Danijela Simonovic, Hymonti Dey, Natascha Johansen, Trude Anderssen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Tor Haug, Morten B. Strøm
Antimicrobial activity and mode of action study of short analogues of the marine antimicrobial peptide Turgencin A 2021 Infection Biology and Antimicrobials (IBA) annual meeting - Hymonti Dey, Danijela Simonovic, Ingrid Sofie Norberg-Schulz Hagen, Terje Vasskog, Elizabeth G. Aarag Fredheim, Hans-Matti Blencke, Morten B. Strøm, Tor Haug
2020
Liposomal delivery of antibiotic loaded DNA nanogels against intracellular infections 2020 Nordic POP Annual Meeting 2020 Conference - Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Pål Jarle Johnsen, Mona Johannessen, Natasa Skalko-Basnet
Liposomal delivery of Nucleic Acid Nanogels to Enhance Entrapment Efficiency and Sustain Release of Antibiotics against Staphylococcal intracellular infections 2020 CRS2020 virtual annual meeting - Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Mona Johannessen, Natasa Skalko-Basnet
2019
Stand på forskningstorg under Utforsk UiT, Forskningsdagene 2019 2019 Utforsk UiT 2019 - Elizabeth G. Aarag Fredheim, Jonina Gudmundsdottir
Hunting new targets to prevent infections - A novel approach to bacterial surface shaving 2019 IBA annual meeting - Runa Wolden, Maria Pain, Roger Karlsson, Anders Karlsson, Elizabeth G. Aarag Fredheim, Jorunn Pauline Cavanagh
På jakt etter nye målsete for behandling av Staphylococcus haemolyticus-infeksjonar: Opp- regulering av sentrale virulens- og adhesjonsprotein hos S. haemolyticus ved kolonisering av humane keratinocyttar 2019 Bioingeniørkongressen - Runa Wolden, Maria Pain, Roger Karlsson, Anders Karlsson, Elizabeth G. Aarag Fredheim, Jorunn Pauline Cavanagh
Gentamicin collateral sensitivity of ciprofloxacin resistant Escherichia coli is opposed by the rapid development of gentamicin resistance 2019 IBA Forskerskole Årsmøte - Elizabeth G. Aarag Fredheim, Nicole Podnecky, Angie Carola Alarcon Rios, Jessica Nguyen Tran, Chantal Verstappen, Klaus Harms, Vidar Sørum, Pål Jarle Johnsen
2018
How to blast a biofilm 2018 Forskningsdagene 2018 - Sören Abel, Anel Mahmutovic, Aaron Nicholas Gillman, Aime Manzi, Natasha-Anne Robson Moe, Silje Lauksund, Øyvind Lorentzen, Elizabeth Aarag, Julia Maria Kloos, Kristin Hegstad, Pauline Cavanagh, Christina Bleis, Merete Storflor
2017
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in an in vivo mouse peritonitis model and an ex vivo human whole blood model 2017 Konferanse - Hildegunn Norbakken Granslo, Elizabeth Aarag, Claus Andreas Klingenberg, Claus Moser, Eirin Esaiassen, Jorunn Pauline Cavanagh, Lars Christophersen, Tom Eirik Mollnes, peter østrup jensen, Trond Flægstad
Antibacterial marine natural product mimics for treatment of infections. 2017 The 8th International Conference on Marine Bioprospecting (BIOPROSP 2017) - Ekaterina Mishchenko, Elizaveta Igumnova, Johanna U Ericson Sollid, Hans-Matti Blencke, Reidunn Silje Lauksund, Tor Haug, Elizabeth Aarag, Morten B. Strøm, Klara Stensvåg
2016
Antibacterial studies of compounds inspired by marine natural products 2016 Cooperation programme in Fisheries and Marine Sciences - Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Johanna U Ericson Sollid, Elizabeth Aarag, Tor Haug, Morten B. Strøm, Klara Stensvåg
2015
Antimicrobial studies of Marine Natural Product Mimics (MNPMs) 2015 The 7th International Conference on Marine Bioprospecting (BIOPROSP 2015) - Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Elizabeth Aarag, Johanna U Ericson Sollid, Tor Haug, Morten B. Strøm, Klara Stensvåg
2014
Antimicrobial and anti-biofilm studies of Marine Natural Product Mimics 2014 MabCent Science day - Ekaterina Mishchenko, Elizaveta Mikhailovna Igumnova, Johanna U Ericson Sollid, Elizabeth Aarag, Hans-Matti Blencke, Tor Haug, Morten B. Strøm, Klara Stensvåg
In vitro studies of the activities of marine natural product mimics on Stapylococcus epidermidis biofilms 2014 The 4th International Symposium on Antimicrobial Peptides AMP 2014 - Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Elizabeth Aarag, Johanna U Ericson Sollid, Tor Haug, Morten B. Strøm, Klara Stensvåg
2013
Antibacterial and anti-biofilm studies of synthetic compounds derived from marine antimicrobial compounds 2013 Bioprosp 2013 - Ekaterina Mishchenko, Elizaveta Igumnova, Hans-Matti Blencke, Johanna U. Ericson Sollid, Elizabeth Aarag, Tor Haug, Morten B. Strøm, Klara Stensvåg
Antibacterial and anti-biofilm activity studies of synthetic compounds inspired by natural bioactive compounds 2013 Seminar series in PhD school “Infection, Inflammation and Immunity” - Ekaterina Mishchenko, Elizaveta Igumnova, Elizabeth Aarag, Johanna U. Ericson Sollid, Hans-Matti Blencke, Tor Haug, Morten B. Strøm, Klara Stensvåg
Antimicrobial biofilm studies of synthetic compounds inspired by marine natural compounds 2013 5th National PhD Conference in Medical Imaging 2013 - Ekaterina Mishchenko, Elizaveta Igumnova, Johanna U. Ericson Sollid, Elizabeth Aarag, Hans-Matti Blencke, Tor Haug, Morten B. Strøm, Klara Stensvåg
Antimicrobial and anti-biofilm activities of novel synthetic compounds based on marine bioactive molecules 2013 The 3rd International Meeting on Antimicrobial Peptides IMAP 2013 - Ekaterina Mishchenko, Elizaveta Igumnova, Elizabeth Aarag, Johanna U. Ericson Sollid, Tor Haug, Hans-Matti Blencke, Morten B. Strøm, Klara Stensvåg